Neuropsychopharmacology – The Influence of Chronic Exposure to Antipsychotic Medications on Brain Size before and after Tissue Fixation: A Comparison of Haloperidol and Olanzapine in Macaque Monkeys

Three groups of six macaque monkeys each were exposed to oral haloperidol, olanzapine or sham for a 17–27 month period…. we observed an 8–11% reduction in mean fresh brain… both drug-treated groups compared to sham animals. The differences were observed across all major brain regions

Neuropsychopharmacology – The Influence of Chronic Exposure to Antipsychotic Medications on Brain Size before and after Tissue Fixation: A Comparison of Haloperidol and Olanzapine in Macaque Monkeys.

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