Category Archives: Chemical Imbalance

Blame it on biology: how explanations of mental illness influence treatment

“The “therapeutic alliance” between clinician and client is a key ingredient in successful treatment, responsible for better clinical outcomes and lower rates of dropout. Biogenetic explanations held by clinicians can impair the therapeutic relationship and those held by clients can impede their recovery.” Nick Haslam

Blame it on biology: how explanations of mental illness influence treatment

▶ Nadine Burke Harris: How childhood trauma affects health across a lifetime – YouTube

▶ Nadine Burke Harris: How childhood trauma affects health across a lifetime – YouTube.

Childhood trauma isn’t something you just get over as you grow up. Pediatrician Nadine Burke Harris explains that the repeated stress of abuse, neglect and parents struggling with mental health or substance abuse issues has real, tangible effects on the development of the brain. This unfolds across a lifetime, to the point where those who’ve experienced high levels of trauma are at triple the risk for heart disease and lung cancer. An impassioned plea for pediatric medicine to confront the prevention and treatment of trauma, head-on.

The new strain of cannabis that could help treat psychosis | Society | The Guardian

Dr David Potter has overseen the production of nearly 2m cannabis plants, mostly for medical research or the production of the cannabis-based multiple sclerosis drug Sativex…

Potter has seen the extreme effects of both substance abuse and schizophrenia in his role as a magistrate for his local court. He recounts a recent case where a seemingly pleasant teenager, suffering from acute and sudden psychotic illness, had turned to alcohol and become violent.  “He ended up smashing someone’s teeth out for not really any reason at all,” says Potter. The defendant, now diagnosed and medicated, will still be found guilty despite his temporary insanity. “In court it just struck me what a nice chap he was.”

The Island Where People Forget to Die – NYTimes.com

The Island Where People Forget to Die – NYTimes.com.

“…their daily routine unfolded much the way Leriadis had described it: Wake naturally, work in the garden, have a late lunch, take a nap. At sunset, they either visited neighbors or neighbors visited them. Their diet was also typical: a breakfast of goat’s milk, wine, sage tea or coffee, honey and bread. Lunch was almost always beans (lentils, garbanzos), potatoes, greens (fennel, dandelion or a spinachlike green called horta) and whatever seasonal vegetables their garden produced; dinner was bread and goat’s milk. At Christmas and Easter, they would slaughter the family pig and enjoy small portions of larded pork for the next several months… “

Schizophenia Is Not What It Used to Be | Psychology Today

Does schizophrenia have genetic roots? …the best that geneticists have done is to identify 128 gene alleles (variants) that are “associated” with schizophrenia. This means that these gene variants might be “risk factors” for schizophrenia at most, but they scarcely can be thought of as causes.

Schizophenia Is Not What It Used to Be | Psychology Today.

Johnson & Johnson to Pay More Than $2.2 Billion to Resolve Criminal and Civil Investigations | OPA | Department of Justice

“to resolve criminal and civil liability” for “promotion for uses not approved as safe and effective… and payment of kickbacks to physicians and to the nation’s largest long-term care pharmacy provider.” This is the “largest health care fraud settlements in U.S. history, including criminal fines and forfeiture totaling $485 million and civil settlements with the federal government and states totaling $1.72 billion.”

Johnson & Johnson to Pay More Than $2.2 Billion to Resolve Criminal and Civil Investigations | OPA | Department of Justice.

Single dose of antidepressant changes the brain | Science Codex

Their whole-brain network analysis shows that one dose of the SSRI reduces the level of intrinsic connectivity in most parts of the brain. However, Sacher and her colleagues observed an increase in connectivity within two brain regions, specifically the cerebellum and thalamus.

Single dose of antidepressant changes the brain | Science Codex.

Neuropsychopharmacology – The Influence of Chronic Exposure to Antipsychotic Medications on Brain Size before and after Tissue Fixation: A Comparison of Haloperidol and Olanzapine in Macaque Monkeys

Three groups of six macaque monkeys each were exposed to oral haloperidol, olanzapine or sham for a 17–27 month period…. we observed an 8–11% reduction in mean fresh brain… both drug-treated groups compared to sham animals. The differences were observed across all major brain regions

Neuropsychopharmacology – The Influence of Chronic Exposure to Antipsychotic Medications on Brain Size before and after Tissue Fixation: A Comparison of Haloperidol and Olanzapine in Macaque Monkeys.

JAMA Psychiatry | Long-term Antipsychotic Treatment and Brain Volumes

“Conclusions  Viewed together with data from animal studies, our study suggests that antipsychotics have a subtle but measurable influence on brain tissue loss over time, suggesting the importance of careful risk-benefit review of dosage and duration of treatment as well as their off-label use.”

JAMA Network | JAMA Psychiatry | Long-term Antipsychotic Treatment and Brain Volumes:  A Longitudinal Study of First-Episode Schizophrenia.

Amy Cuddy: Your body language shapes who you are – YouTube

Here are practical steps to self empowerment – simple lessons from the neuro-science of posture. Amy’s self disclosure and empathy around 16 minutes in make this a real gem! (Show this to your clients!!!)

Amy Cuddy: Your body language shapes who you are – YouTube.